THE INFLUENCE OF THE HYDRAULIC EFFECT OF THE BLOOD DYNAMICS AT THE EXTRASYSTOLY ON THE MORPHOLOGY OF MAINSTREAM ARTERIES

Abstract

The influence of various types of extrasystole on the change in arterial hemodynamics and the morphology of changes in the wall of the mainstream arterial vessels is not well understood. The purpose of the study was to determine the effects of water hammer on the hemodynamics of the main arteries in various types of extrasystoly. The study was conducted on 228 patients (122 men and 106 women) aged 43 to 76 years, the average age was 62 ± 4.3 years. For the analysis, the data apex-cardiography, daily monitoring by Holter, echocardiography, electrocardiography, sphygmography, color Doppler mapping of the vessels of the head and neck and extremities were compared. Water hammer of extrasystoles leads to mechanical damage to the endothelium of the arterial wall and serves as a trigger for inflammation and activation of the process of neolipogenesis, the formation of the atheroma. Additional hydraulic waves contribute to trauma to the vascular wall, growth and increase in area of atheromas. The described morphological changes in the vascular wall, the authors describe as «water hammer syndrome» and analyze its role and pathophysiological mechanisms of the development of vascular complications at extrasystoles and reconstructive operations on arterial vessels.