Abstract
To investigate the effect of dose calculation grid on calculated dose-volumetric parameters for eye lenses and optic pathways. A total of 30 patients treated using the volumetric modulated arc therapy (VMAT) technique, were retrospectively selected. For each patient, dose distributions were calculated with calculation grids ranging from 1 to 5mm at 1mm intervals. Identical structures were used for VMAT planning. The changes in dose-volumetric parameters according to the size of the calculation grid were investigated. Compared to dose calculation with 1mm grid, the maximum doses to the eye lens with calculation grids of 2, 3, 4 and 5mm increased by 0.2 ± 0.2Gy, 0.5 ± 0.5Gy, 0.9 ± 0.8Gy and 1.7 ± 1.5Gy on average, respectively. The Spearman's correlation coefficient between dose gradients near structures vs. the differences between the calculated doses with 1mm grid and those with 5mm grid, were 0.380 (p < 0.001). For the accurate calculation of dose distributions, as well as efficiency, using a grid size of 2mm appears to be the most appropriate choice.
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