Abstract
The brilliant results of the work of Schaudinn and Hoffman, following the researches of so many able investigators, and confirming pre-existing opinions that syphilis was due to a specific micro-organism, are certainly a cause for congratulation on the progress of pathologic study. To the general practitioner, however, it presents the question: "What advantage is gained and what difference should it make in the management of a case of syphilis at any stage?" This is a pertinent question and deserves consideration. In connection with the recent work done by French investigators in the prophylaxis and treatment of syphilis by calomel ointment and atoxyl, a partial answer to the question is found. Metchnikoff<sup>1</sup>has conclusively shown that syphilis may be aborted by the inunction of calomel ointment, provided it be used sufficiently soon following inoculation. Such a prophylactic use of the ointment, while interesting and useful on rare occasions, is impracticable
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