Abstract
Abstract New chiral iron chelators bearing N-hydroxy-2(1H)-pyrazinone, d-amino acid residues, and tris(2-aminoethyl)amine were synthesized, and their kinetic behavior of iron removal from human transferrin was investigated. The rate of iron removal by the chelator bearing d-alanine residue was suppressed to only one fourth that of l-alanine derivative.
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