The influence of standardized dry ivy leaf extract on the proportion of nasal secretion after post-septoplasty nasal packing removal

Slobodan Savović,Milica Paut Kusturica,Vladimir Kljajić,Maja Buljčik Čupić,Ljiljana Jovančević,Vedrana Pavlović,Aleksandar Rašković

doi:10.1016/j.bjorl.2018.05.005

Slobodan Savović, Milica Paut Kusturica + Show 5 more

Open Access

https://doi.org/10.1016/j.bjorl.2018.05.005

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Abstract

IntroductionAfter post-septoplasty nasal packing removal, a certain proportion of nasal secretion occurs, leading to local and sometimes systemic infections. ObjectiveThe aim was to determine if standardized dry ivy leaf extract application after nasal packing removal influences the reduction of nasal secretion and diminish the occurrence of local infections. MethodsThe study included 70 post-septoplasty patients (divided into two equal groups) whose nasal packing was removed on the third day after the procedure. Group I was treated with standardized dry ivy leaf extract syrup along with regular nasal irrigation for the five days after the nasal packing removal whereas the Group II had only nasal lavage. On the sixth day after nasal packing removal, the quantity of nasal secretion was determined using a visual analog scale and nasal endoscopic examination. ResultsThe group treated with standardized dry ivy leaf extract syrup had significantly lesser nasal secretion both by subjective patients’ assessment (p<0.001) and by nasal endoscopic examination (p=0.003). The post-surgical follow up examination on the sixth day after nasal packing removal showed no development of local infection in the Group I, while in the Group II a local infection was evident in five patients (14.29%) and antibiotic therapy was required. ConclusionThe use of the standardized dry ivy leaf extract after nasal packing removal significantly lowers the proportion of nasal secretion.

Highlights

After post-septoplasty nasal packing removal, a certain proportion of nasal secretion occurs, leading to local and sometimes systemic infections
The aim of this study was to explore whether the use of secretolytics after post-septoplasty nasal packing removal influences the proportion of nasal secretion, as well as whether the use of secretolytics has an impact on local infection occurrence of the nose and the paranasal sinuses in the post-surgical period in which the use of antibiotics was indicated
Higher values in nasal secretion subjective assessment were registered on the sixth post-surgical day in Group II in comparison with group I (Z = 4.188, p < 0.001) (Table 1)

Summary

Introduction

After post-septoplasty nasal packing removal, a certain proportion of nasal secretion occurs, leading to local and sometimes systemic infections. Objective: The aim was to determine if standardized dry ivy leaf extract application after nasal packing removal influences the reduction of nasal secretion and diminish the occurrence of local infections. Group I was treated with standardized dry ivy leaf extract syrup along with regular nasal irrigation for the five days after the nasal packing removal whereas the Group II had only nasal lavage. On the sixth day after nasal packing removal, the quantity of nasal secretion was determined using a visual analog scale and nasal endoscopic examination. Results: The group treated with standardized dry ivy leaf extract syrup had significantly lesser nasal secretion both by subjective patients’ assessment (p < 0.001) and by nasal endoscopic examination (p = 0.003). No significant difference was found between the patients who underwent nasal packing and the patients who did not in terms of post-surgical bleeding, occurrence of nasal septum hematomas and post-surgical adhesions.3---5 Bernardo et al concluded that routine anterior nasal packing was not beneficial and that it can increase morbidity and potential complications.[6]

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