Abstract
The toxicity of potassium ferrocyanide (PFC) and sodium nitroprusside (SNP) and protective effects of 2.4–dinitrophenol (DNP) under PFC or SNP treatment were tested on the Drosophila melanogaster model system. Fly larvae were bred on food supplemented with PFC or SNP at concentrations of1.0 mM and mixtures with DNP in concentrations of 0.50 and1.25 mM, either alone or in combination with1.0 mM PFC or SNP. Larval treatment with PFC or SNP resulted in higher uric acid and lower triglycerides content in adult flies, while DNP in mixtures with PFC or SNP relieved these effects. Furthermore, SNP treatment resulted in lower ALT and AST activities either alone or in mixtures with DNP. The potential mechanisms of protective DNP effects against PFC or SNP toxicity are discussed.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
