Abstract
Inhibitor adsorption as a means of reducing crystal growth rates is an area of extreme interest, not only in the prevention of industrial scale formation, but also in the field of biomineralization, especially in urolithiasis research. An investigation of the role of serum and its chief macromolecular component, albumin, in the inhibition of calcium oxalate monohydrate crystal growth in vitro, was carried out by a series of adsorption studies paralleled with constant composition potentiostatic crystallization kinetics reactions. The data indicate albumin as an effective crystallization inhibitor for this system, adsorbing through electrostatic interactions onto the charged crystalline surface.
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