Abstract
The cat, albeit an expensive animal to breed and maintain, affords a relatively large eye ideal for studies on the embryonic retina. This study reports on the efficacy of serial removal of feline foetuses for studies on the histogenesis of the retina. Single feline foetuses were serially removed from the uterus of pregnant cats to determine if there were histologic changes in the foetal retina of the remaining foetuses during subsequent development. The retinas of neonates from mothers that had undergone hysterotomies were compared by light and transmission electron microscopy to those from animals whose mother's had not had hysterotomies. No histologic differences in the retinas were detected between the 2 groups. The duration of gestation was unaffected. This study indicates that it is possible to obtain embryonic retinal tissue at more than one stage of development from the same pregnant female without inducing histologically observable anomalies.
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