Abstract

of 50:1 and 25:1 were significantly higher in vitamin D low group when compared with those of vitamin D normal group (P<0.05 each). No significant differences were observed between the vitamin D low group and the vitamin D normal group in the percentage of CD3+ T and CD3-CD56+ NK cells, CD3+CD4+ T cells, CD3+CD8+ T cells, the proportion of IFNexpressing Th cells and NK cytotoxicity at E:T ratio of 12.5:1. Conclusions: These observations suggest that low vitamin D level may increase the risk of cellular immune abnormalities of womenwith RM. Our data provide evidence that vitamin D supplementation might be as a new possible therapeutic option for women with RM and cellular immune abnormalities.

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