Abstract
Aim. To study an interrelation between obstructive sleep apnea syndrome with lipid metabolism disorders and atherosclerotic lesion of carotid arteries in patients with arterial hypertension. Material and methods. The article presents the results on the study of 150 patients with arterial hypertension, of those 75 also had obstructive sleep apnea syndrome (main group); 75 patients without apnea constituted control group. This study included patients with variable body mass index — from normal values (18,5-24,9 kg/m 2 ) to 2-3 grade obesity. Results. A reliable correlation interrelation was found for the sleep apnea episodes quantity during the night and risk of different types of hyperlipidemias, with intima\ media thickness in carotid arteries.
Highlights
It is ascertained that in the main group prevalence of dyslipidemias of IIa and IIb types is higher as atherosclerotic lesion
Более значимые кардиоваскулярные события встречаются у лиц мужского пола до 70 летнего возраста [1, 2], в отличие от пациентов пожилого возраста [3]
Summary
Aim. To study an interrelation between obstructive sleep apnea syndrome with lipid metabolism disorders and atherosclerotic lesion of carotid arteries in patients with arterial hypertension. Исследования, проведенные в течение последних 15 лет, доказали, что синдром обструктивного апноэ сна (СОАС) способствует развитию и является причиной эндотелиальной и сосудистой дисфункции, которая ведет к раннему началу атеросклероза и повышению риска преждевременных случаев кардиоваскулярных событий. В связи с вышеизложенным представляется актуальным проведение исследования по влиянию СОАС на развитие асимптомного поражения сонных артерий у пациентов с АГ, имеющих различный диапазон индекса массы тела (ИМТ): нормальный, повышенный ИМТ, ожирение.
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