The Influence of Nighttime Protein Intake on Overnight Lipolysis and Next Morning Fat Oxidation

Abstract

PURPOSE: Determine in overweight and obese men if casein (CAS, 30 g protein), as compared to a non-caloric placebo (PLA), consumed before bed would alter blood markers but elicit similar changes in overnight subcutaneous abdominal adipose tissue (SCAAT) lipolysis and next morning whole-body fat oxidation. METHODS: Determine in overweight and obese men if casein (CAS, 30 g protein), as compared to a non-caloric placebo (PLA), consumed before bed would alter blood markers but elicit similar changes in overnight subcutaneous abdominal adipose tissue (SCAAT) lipolysis and next morning whole-body fat oxidation. RESULTS: There were no differences between treatments in overnight SCAAT glycerol (CAS, 175.0±26.5; PLA, 184.8±20.7 μmol/L; p=0.77), next morning fat oxidation (CAS, 0.76±0.01; PLA, 0.76±0.01; p=0.75) or metabolic rate (CAS, 2126±111; PLA, 2145±106 kcals/day; p=0.94). Similarly, there were no differences in any blood markers; however, the participants were hyperinsulinemic (fasting insulin > 30 μUL) prior to the study. CONCLUSION: SCAAT lipolysis and next morning fat oxidation, metabolic rate and blood markers were similar between CAS and PLA. CAS before bed did not promote fat storage and may help with long-term weight control. Supported by FSU and Dymatize® Nutrition.