The influence of metabolic syndrome in the outcomes of colorectal cancer patients

Abstract

AimsDetermine the influence of metabolic syndrome and its different components in the outcomes of colorectal cancer surgery at 30days. Materials and methodsProspective study that included all patients submitted to elective colorectal cancer surgery between August 2015 and August 2016 at Hospital de Braga. Clinical and laboratory parameters evaluated pre-operatively were: central obesity, blood pressure, fasting glucose, triglycerides levels and HDL cholesterol levels. Any complications during the first 30-days after surgery were recorded (readmission, reintervention, anastomotic dehiscence, morbimortality). ResultsOne hundred and thirty-four patients were included. Metabolic syndrome was diagnostic in 40.7% of patients with the ATPIII definition, 67.5% with the AHA definition and 67.0% with the IDF definition. At 30days after colorectal cancer surgery, 73.1% patients don’t have any complication, 15.7% have minor complications (grade I/II of Clavien-Dindo classification), 11.1% have major complications (grade III/IV/V of Clavien-Dindo classification) and 1.5% have died from surgical complications (grade V of Clavien-Dindo classification). The statistic analysis didn’t reveal any association between MS, or it’s different components, and surgical outcomes. ConclusionThis study seems to indicate that metabolic syndrome don’t have any influence in surgical outcomes of colorectal cancer surgery.