Abstract
The present study examines the influence of oxygen tension on the recurrent tidal volume changes caused by oscillations in arterial Pa O 2 . The oscillations have a period equal to two respiratory cycles, and are produced by giving alternately CO 2-enriched and CO 2-free gas mixtures. The results show alternation of the tidal volume with the same incidence (> 50%) at low, normal and high oxygen tensions. However, the magnitudes of the breath-by-breath changes are significantly greater at low oxygen tension than at normal oxygen tension. Under high oxygen tension breath-by-breath tidal volume changes are indistinguishable from those at normal oxygen tension.
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