Abstract
Background: Significant (>70%) extracranial stenosis of the internal carotid artery (ICA) is a known risk factor for brain damage in patients with coronary heart disease (CHD) undergoing coronary artery bypass grafting (CABG). There is no clear evidence of the low and moderate ICA stenoses influence on the neurophysiologic status of patients after CABG. This work was aimed at studying the influence ICA stenoses (<50%) on the dynamics of neurophysiologic status in patients undergone CABG. Methods: We examined neurophysiologic functions and electroencephalograph in CHD patients (N = 45) aged from 45 to 70 years. All patients were divided into two groups: with ICA stenosis (n = 20) and without one (n = 25). Results: It was established that the group ICA stenosis had a negative dynamics of neurophysiologic status 6 months follow-up after CABG compared with patients without stenosis. Conclusion: Our results suggest that the presence of low and moderate ICA stenosis is one of the factors affecting the neurophysiologic status of CHD patients. It has been assumed that the patients with ≤50% ICA stenoses constitute a high-risk group for cerebral complications after on-pump CABG.
Highlights
In the last decade one of the most discussable issues are the cerebral complications after coronary artery bypass grafting (CABG) due to its high social importance and the data ambiguity
It was established that the group internal carotid artery (ICA) stenosis had a negative dynamics of neurophysiologic status 6 months follow-up after CABG compared with patients without stenosis
Our results suggest that the presence of low and moderate ICA stenosis is one of the factors affecting the neurophysiologic status of coronary heart disease (CHD) patients
Summary
In the last decade one of the most discussable issues are the cerebral complications after coronary artery bypass grafting (CABG) due to its high social importance and the data ambiguity. It was established that elderly patients in the age ≥70 years are high-risk group and have a higher incidence of adverse cerebral outcomes. Significant (>70%) extracranial stenosis of the internal carotid artery (ICA) is a known risk factor for brain damage in patients with coronary heart disease (CHD) undergoing coronary artery bypass grafting (CABG). There is no clear evidence of the low and moderate ICA stenoses influence on the neurophysiologic status of patients after CABG. Results: It was established that the group ICA stenosis had a negative dynamics of neurophysiologic status 6 months follow-up after CABG compared with patients without stenosis. Conclusion: Our results suggest that the presence of low and moderate ICA stenosis is one of the factors affecting the neurophysiologic status of CHD patients. It has been assumed that the patients with ≤50% ICA stenoses constitute a high-risk group for cerebral complications after on-pump CABG
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