The Influence of Load Carriage on Knee Joint Loading and Metabolic Cost on Walking with Lower-Limb Amputation: A Preliminary Modeling Study

Abstract

ABSTRACT Introduction For able-bodied individuals, the mechanical output from the ankle muscles is modulated to meet the altered demands of load carriage. However, for individuals with a lower-limb amputation, the stiffness properties of standard-of-care prosthetic feet do not change with varying load conditions. Thus, individuals with amputation often develop gait asymmetries during load carriage that increase their risk for developing overuse injuries such as in the intact knee and increase the metabolic cost of walking relative to able-bodied individuals. The purpose of this preliminary study was to assess the influence of load carriage technique on knee joint loading and metabolic cost during gait of an individual with a below-knee amputation using a forward dynamics simulation framework. Methods Simulations were generated to track the experimental walking data of individuals with amputation for 3 loading conditions (unloaded, front load, and back load). Results These simulations showed that individuals with amputation rely on their intact limb as a compensatory strategy to meet the increased demands of carrying a load. Carrying a back load was found to increase intact knee joint loading relative to carrying a front load but reduced metabolic cost. Conclusion The tradeoff between joint loading and metabolic cost should be considered when determining the appropriate load carriage technique. Future work should focus on improving prosthetic foot designs to help reduce joint loading asymmetry and elevated metabolic cost during different loading conditions for individuals with lower-limb amputation.