Abstract
Summary. An influence of normobaric hypoxic (10 % of oxygen in nitrogen) and hyperoxic (40 % of oxygen in nitrogen) breathing sessions on the respiratory part of the lungs was investigated in rats of 3 month of age. After 28 daily hypoxic sessions, 30 min each, we detected lung hyperinflation, an enlargement of the total alveolar area and reduction in connecting tissue elements in the lungs. After 28 daily hyperoxic sessions, 60 min each, we found reduction in mean diameter, depth, cross-sectional area and the entrance size of alveoli, increased the amount of collagen fibers, the alveolar wall thickness and increased oxyproline concentration in the lungs. These findings could indicate the connecting tissue growth in the respiratory part of the lungs and worsening of oxygen diffusion through the blood-air barrier.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
