Abstract
<p>The urgency of the problems caused by frequent research septic complications in patients with acute calculous<br />cholecystitis (ACC), accompanied by increase of endogenous intoxication. The study involved patients with ACC<br />complicated with choledocholithiasis, acute cholangitis and local peritonitis. The studies found an increase in levels of<br />total serum bilirubin in all groups due to direct fraction, indicating obstructive jaundice. The increase ratio of bilirubin<br />monoglyukuronid/diglucuronide more than 1.0 in septic complications of ACC indicate liver parenchyma lesion and<br />growth of endogenous intoxication. The reduction in serum total protein content by reducing the concentration of<br />albumin in the blood and decrease the reactivity of the organism with the increase of endogenous intoxication in<br />patients with septic complications is observed.</p>
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