Abstract

Falciparum malaria is a leading cause of morbidity and mortality in endemic regions of the world. In areas of intense transmission of P. falciparum children less than the age of 5 years are the most susceptible to severe malaria. The complex interactions between the parasite the human host the vector and environment or social factors may influence the outcome of a malaria infection (White & Ho 1992). Control measures have been based on wide-scale attempts at the reduction in transmission with anti-vector measures and therapeutic management of clinical disease. In sub-Saharan Africa however control is mainly focused on management of the clinical disease and more recently on the use of intermittent preventive treatment (IPT) in pregnant women. Individual preventive measures such as the use of mosquito repellants and the use of insecticide treated bed nets (ITNs) and curtains also influence the risk of host-vector contact host infection and consequently mortality especially in children susceptible to the severe forms of the disease. (excerpt)

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