Abstract
<h3>B. ANIMAL EXPERIMENTATION</h3><h3>TRANSPLANTED TUMORS</h3> In the period of active investigation of transplantable tumors in animals that followed the demonstration by Leo Loeb and by Jensen that series inoculation of rat and mouse tumors is readily carried out, there was naturally not a little study of the influence of heredity on the inoculated tumors. At this time it was not so fully appreciated as it now is that an inoculated tumor is something quite different from a spontaneous tumor. A transplanted tumor differs from a spontaneous tumor fundamentally in that it is never a growth of the cells of the inoculated animal, but it is a growth of the cells descended from the mouse that furnished the original spontaneous tumor from which the transplanted growth was obtained. For example, a mouse inoculated with a strain of the Jensen carcinoma, which has been carried through myriads of generations of transplants during
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