Abstract
The effect of glucose upon the transport of light in tissue-simulating phantoms is shown and its possible application for non-invasive glucose monitoring in diabetic patients is discussed. Here, the authors investigate the physical background of this effect. The presence of glucose in an aqueous solution increases its refractive index and therefore has an influence upon the scattering properties of particles suspended in solution. Experimental data on the effect of glucose upon the scattering coefficient and the phase function of aqueous suspensions of spherical polystyrene particles are presented for near-infrared wavelengths and compared to values predicted by Mie theory. The subsequent effect upon light transport in multiple scattering, tissue-simulating phantoms is demonstrated experimentally in a slab geometry and theoretically by applying diffusion theory. It is furthermore shown that optional measurements in the frequency domain allow changes of absorption and scattering coefficient to be separately determined. The possible magnitude of this glucose effect in tissue in vivo is discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
