Abstract
The perspectives of geography and medicine are integrated to analyze the influence of geographic factors on the reference value of tumor marker CYFRA21-1, and explore the spatial distribution of tumor marker CYFRA21-1 for healthy adults in China; CYFRA21-1 is a tumor marker for adults in different regions of China. The value of medical diagnosis provides a theoretical basis. Based on the measured values of the tumor marker CYFRA21-1 in 24,634 healthy adults in 314 cities, combined with 15 geographical factors, predictive modeling was carried out through spatial autocorrelation, correlation analysis, ridge regression analysis, and support vector machine, and the health of 2322 cities in China was predicted. The reference value of the tumor marker CYFRA21-1 for healthy adults in China was used to generate a geographical distribution map. The results showed that the distribution of reference values of the tumor marker CYFRA21-1 for healthy adults in China showed a higher trend in northern and northwestern areas, and a lower trend in southern areas. The reference value of tumor marker CYFRA21-1 has a certain concentration in the geographical distribution of China, and temperature, precipitation, wind speed, and soil factors will affect the reference value of CYFRA21-1 of healthy adults in China.
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