The influence of different usage of dyclonine hydrochloride mucilage on hemodynamics and postoperative throat pain of laryngeal mask anesthesia patients

Abstract

Objective To investigate influence of different usage of dyclonine hydrochloride mucilage on hemodynamics and postoperative throat pain of laryngeal mask anesthesia patients. Methods Sixty patients in flexible ureteroscopic holmium laser lithotripsy with laryngeal mask anesthesia were randomly divided into three groups according to different usage of dyclonine hydrochloride mucilage(n=20). Group A was coated laryngeal mask with paraffin oil. Group B was coated laryngeal mask with dyclonine hydrochloride mucilage. Group C was coated laryngeal mask with dyclonine hydrochloride mucilage and dyclonine hydrochloride mucilage gargle. The indwelling time of laryngeal mask, postoperative recovery time of spontaneous breathing, time of hearing the call to open eyes, and the time of pulling out the laryngeal mask were recorded. Heart rate (HR), mean blood pressure (MBP) index at T1 (pre-anesthesia induction), T2 (1 min before pulling out the laryngeal mask), T3 (pulling out the laryngeal mask), T4 (5 min after removing the laryngeal mask ), and T5 (10 min after removing the laryngeal mask ) were recorded. The complications of throat after removing laryngeal mask were observed. The pain degree of sore-throat at the time of 30 minutes after removing the laryngeal mask was observed. The adverse reactions of the usage of dyclonine hydrochloride were observed in three groups. Results There were no statistically significant differences in indwelling time of laryngeal mask, postoperative recovery time of spontaneous breathing, time of hearing the call to open eyes, and the time of pulling out the laryngeal mask among three groups (P>0.05). There were no statistically significant differences in HR, MBP at T1,and T5 (P>0.05). HR and MBP were higher in group A than in groups B and C at T2~T4,and HR and MBP were higher in group B than in group C at T2~T4,with statistically significant difference (P 0.05). The pain degree of sore-throat in group C were significantly lower than in group B, and the pain degree of sore-throat in groups B and C was significantly lower than in group A (P<0.05). There were no allergic reactions and local anesthetic poisoning for three groups. Conclusions Dyclonine hydrochloride mucilage can reduce hemodynamic fluctuations during recovery period, and prevent or relieve effectively the patient's throat pain after laryngeal mask anesthesia. At the same time, dyclonine hydrochloride mucilage can improve the patient's postoperative physical comfort without adverse reactions, especially coated laryngeal mask with dyclonine hydrochloride mucilage and dyclonine hydrochloride mucilage gargle. Key words: Propiophenones/AD; Gels; Laryngeal masks; Hemodynamics; Anesthesia, general; Pain, postoperative/DT