The influence of different resection range on prognosis of patients with gastric cancer in M area

Abstract

Objective To compare the survival rate and recurrence between the patients with gastric cancer in M area treated with radical total gastrectomy and radical distal subtotal gastrectomy. Methods Data of 106 cases of the patients with gastric cancer in M area were analyzed retrospectively from March 2007 to March 2008 in Department of Gastric Surgery in Liaoning Cancer Hospital. 55 cases treated by radical total gastrectomy (total gastrectomy group) and 51 cases by distal subtotal gastrectomy (subtotal gastrectomy group). Differences of postoperative local recurrence rates and 1, 3, 5-year survival rates between both groups were compared. Results The anastomotic recurrence rate of total gastrectomy group was lower than that of subtotal gastrectomy group (3.64 % vs 17.65 %, P=0.018), the intraperitoneal recurrence rate was also lower (25.45 % vs 45.10 %, P=0.034). The postoperative 1-year survival rates of total gastrectomy group and subtotal gastrectomy group were 92.73 % and 88.24 %, 3-year survival rates were 74.55 % and 66.67 %, the 5-year survival rates were 58.18 % and 35.29 %, respectively. The differences of 1, 3-year survival rates did not show statistical significance (P>0.05), while that of the 5-year survival rates showed statistical significance (P=0.018). Conclusion For gastric cancer in M area, total gastrectomy is recommended for the treatment, which is helpful to reduce the local recurrence rate and improve the 5-year survival rate. Key words: Stomach neoplasms; M area; Surgery