Abstract
A crude alkaline extract of anterior hypophyseal lobe was injected over a short period into two groups of rats, one receiving a 15 per cent zein diet which did not support growth, and the other a similar diet fortified with sufficient tryptophan and lysine to make it capable of supporting growth. The depression of urinary N output caused by the injections was of similar magnitude for both groups. It had been concluded that the mechanism causing N retention is not necessarily associated with the process of growth.
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