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Abstract
The purpose of this investigation was to show that the amount of calcium in the intake induced definite changes in the thyroid gland of the rat under specific conditions. The experiments were devised to meet certain objections arising from former work concerned with the effect of rachitogenic diets on the thyroid gland of the albino rat (18). The results of that study indicated that the addition of calcium carbonate to diets deficient in iodine resulted in an enhancement of the degree of hyperplasia. Since there was a considerable variation found in the degree of hyperplasia within similar experimental groups, the above statement might be challenged. The possibility that markedly hyperplastic changes might have been encountered if a larger number of glands from rats on iodine-deficient diets containing lesser amounts of calcium had been examined, has to be considered. The influence of new cereals may have been a contributing factor. Furthermore, the animals on low iodine diets may have been affected by th...
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