Abstract

The excretion of FSH, LH and 17-ketosteroids was studied in healthy men before, during and after administration of antiandrogens, i.e. cyproterone-acetate and cyproterone. The first compound mainly decreased the FSH-activity and to a lower extent also the LH-activity in cases with comparatively high pretreatment levels, but did not clearly affect these hormones in other subjects. The excretion of 17-ketosteroids was not much altered. In contrast the free alcohol, cyporoterone, tended to increase the FSH- and LH-levels in some, the 17-ketosteroids in all cases.

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