Abstract
Background: Anatomical spaces are defined by the author as permanently present spaces in the body and are further categorised into true and physiological. True anatomical spaces are formed by the borders of other structures, while physiological anatomical spaces are of hollow viscera. This study aims to investigate the influence of true and physiological anatomical spaces on cancers associated with a poor prognosis, specifically their role in causing diagnostic delay, asymptomatic disease progression and presentation at advanced stages.
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