Abstract
Intensive, uncontrolled, long term usage of industry originated Bifidobacterium animalis subspecies lactis by humans lead the “Probiotic contamination” of human gut, when unusual, not common for healthy individuals bacterial colonies have being created and dominate for a long time, changing the function of Human Microbiome. Several strains of Bifidobacterium animalis subspecies lactis (produced by few leading world biotechnological manufacturers) colonize human mucosa surfaces, lead the SARS-CoV-2 increased ability to penetrate Air path and gastrointestinal mucosa surfaces, change an innate immunity of individuals, infect human cells and ensure specific complications, as cytokine storm, atypical pneumonia, clotting. SARS-CoV-2 features (as interaction with ACE2 protein, others possible cell-entry points, binding to human cell surface and endocytosis) are enhanced by above bacterial metabolites. Further on, Bifidobacterium animalis subspecies lactis or metabolically similar one, provide deregulated release of pro and anti-inflammatory cytokines, lead a severe course of COVID-19.
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