Abstract
Continuous external gamma radiation throughout life at the rate of 0.062 rad/day failed to induce leukemia in A/Jax mice, but did in 55% of RAP mice. Sixty percent were lymphatic, 23% myelogenous, and 17% of other types of leukemia. In RAP mice there was no significant shift in frequency of leukemia in each of five successive generations. The experimental mice were compared with mice irradiated from an internal radiation source and also controls. The incidence of leukemia in control mice was 7%. The high incidence of leukemia in this irradiated population cannot be explained, but the probability is strong that the population evolved from highly leukemia-susceptible mice.
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