Abstract
Experiments were undertaken to assay for the induction of antibody reactivity to endogenous viral glycoprotein of subgroup E in 15I 5 × 7 2 chickens infected with Pr-A sarcoma virus. Antibody in the sera of the sarcomatous chickens was marginally reactive to the envelope glycoprotein of exogenous viruses of subgroups other than A, but more strongly reactive to the envelope glycoprotein of both the subgroup A infecting virus and the endogenous tumor virus RAV-0. This pattern of reactivity was distinct from the patterns determined in earlier studies with Pr-A-infected chickens which differed from 15I 5 × 7 2 in expression of endogenous viral envelope-related glycoprotein.
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