Abstract
Copyright: © 2012 Pioli G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Proximal myopathy and muscular weakness are one of the hallmarks of severe osteomalacia, together with the defective mineralization of newly formed bone matrix and bone pain [1]. Muscles biopsy studies have demonstrated that prolonged Vitamin D deficiency may produce a selective atrophy of type 2 muscular fibers, which are characterized by short, fast bursts of power and rapid fatigue [1].
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