Abstract

Background and Aims : To determine the incidence of visceral obesity and the severity of adipose tissue dysfunction in patients with arterial hypertension (AH) and NAFLD.Methods: A prospective controlled study involving 120 hypertensive patients with and without NAFLD was carried out.Anamnesiscollection,measurement of anthropometric parameters,body mass index (BMI), waist-to-hip ratio,and visceral obesity index (VOI) calculations (with the age norm for the studied group of patients being≤1.92 conventional units) and epicardial fat thickness were carried out.Also,the degree of adipose tissue dysfunction (ATD) and visceral fat percentage were determined using the bioelectrical impedance method.Results: For a number of demographic and clinical parameters the comparison groups were comparable (p>0.05). When calculating the visceral obesity index,a significantly higher number of patients with VOI>1.92 was observed in patients with AH and NAFLD compared to patients with isolated AH (91.4% vs 40.9%,p=0.0000).As a result of assessing the degree of ATD in the main group, the following data were obtained:moderate ATD-20%,significant ATD-42.8%, severe ATD-28.5%(p=0.5361;p=0.1215;p=0.6281,respectively). At the same time,the percentage of visceral fat in the first group was significantly higher compared to the second group (12[11:14.5] vs 9[6:9],p=0.0000).94.2% of patients in the AH+NAFLD group had the waist-to-hip ration higher than the accepted norm,compared to 54.4% of patients in the AH group (p=0.0004).The epicardial fat thickness was also higher in patients with comorbid pathology (5,3[4,0-7,5] vs 3,0[2,5-3,5],p=0.0000).There is a significant increase in BMI in the first group compared to the second group (32[30.3:34.2] vs 27[24.5:28.7],p=0.0000).Conclusions: Patients with AH and NAFLD have a significantly higher visceral obesity index compared to patients with isolated AH. Background and Aims : To determine the incidence of visceral obesity and the severity of adipose tissue dysfunction in patients with arterial hypertension (AH) and NAFLD. Methods: A prospective controlled study involving 120 hypertensive patients with and without NAFLD was carried out.Anamnesiscollection,measurement of anthropometric parameters,body mass index (BMI), waist-to-hip ratio,and visceral obesity index (VOI) calculations (with the age norm for the studied group of patients being≤1.92 conventional units) and epicardial fat thickness were carried out.Also,the degree of adipose tissue dysfunction (ATD) and visceral fat percentage were determined using the bioelectrical impedance method. Results: For a number of demographic and clinical parameters the comparison groups were comparable (p>0.05). When calculating the visceral obesity index,a significantly higher number of patients with VOI>1.92 was observed in patients with AH and NAFLD compared to patients with isolated AH (91.4% vs 40.9%,p=0.0000).As a result of assessing the degree of ATD in the main group, the following data were obtained:moderate ATD-20%,significant ATD-42.8%, severe ATD-28.5%(p=0.5361;p=0.1215;p=0.6281,respectively). At the same time,the percentage of visceral fat in the first group was significantly higher compared to the second group (12[11:14.5] vs 9[6:9],p=0.0000).94.2% of patients in the AH+NAFLD group had the waist-to-hip ration higher than the accepted norm,compared to 54.4% of patients in the AH group (p=0.0004).The epicardial fat thickness was also higher in patients with comorbid pathology (5,3[4,0-7,5] vs 3,0[2,5-3,5],p=0.0000).There is a significant increase in BMI in the first group compared to the second group (32[30.3:34.2] vs 27[24.5:28.7],p=0.0000). Conclusions: Patients with AH and NAFLD have a significantly higher visceral obesity index compared to patients with isolated AH.

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