The Incidence and Predictors of Renal artery Stenosis in Patients Referred for Coronary Angiography

Abstract

Background: Renal artery stenosis (RAS) and coronary artery disease (CAD) are two manifestations of a same pathogenesis which is atherosclerosis.. RAS is a leading factor of secondary hypertension, ischemic nephropathy and end stage renal disease (ESRD). Aim of work: This study was aimed to detect the incidence and predictors of renal artery stenosis in patients referred for elective coronary angiography. Patients and Methods: In this study we included 100 patients who underwent coronary and renal angiography.The mean age was 56.6 + 7.9 years, 60 males (60%), 40 females (40%), 60 diabetic (60%), 58 hypertensive (58%), 41 smokers (41%), 62 dyslipidemic (62%), 27 patients with family history of ischemic heart disease (27%), and patient with normal coronaries 12 (12 %). Our study consisted of 2 groups; 87 (87%) patients with normal renal arteries (group 1) and 13 (13%) patients with renal artery stenosis (group 2). Results: The incidence of RAS was 13% and the incidence of significant RAS (>50% stenosis) was 7%. The significant difference between the two groups was in the terms of hypertension (p-value 0.014), female gender (p-value 0.021), multivessel (> 2 vessels) coronary artery disease (p-value 0.046), normal coronaries had a significant negative association with RAS (p-value 0.027) and there was a significant relationship between atherosclerotic involvement of Left anterior descending artery (LAD), Diagonal, and right coronary artery (RCA) with RAS (p-value 0.037, 0.041 and 0.042). Conclusion: It could be concluded that predictors of RAS were hypertension, multivessel coronary artery disease (> 2 vessels) and female gender.