Abstract
ABSTRACT Explanted cartilage from can/can mice aged 3 days shows increased protein and mucopoly-saccharide synthesis. Injection of [U-14C]glucose into 3-day-old can/can mice failed to duplicate the increased mucopolysaccharide formation. Transplanted can/can tail vertebrae grown in the renal capsule of normal sibs grew less well than those from normal litter-mates’ also suggest-ing that the increased metabolism seen in vitro is not a feature of in vivo development.
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