Abstract
The in vitro O2-consumption of kidney slices from normal and sublimate intoxicated rats has been studied by means of Warburg's method. It has been demonstrated previously that the weight of kidneys from sublimate intoxicated rats varies with a positive linear correlation to urine output. the traditional units of Warburg's method, in which O2-consumption is related to dry weight or any known constituent of the investigated tissue, were not suitable for the present experiment. A new unit is therefore introduced, and is defined as microliter O2-consumption in kidneys per g body weight per hour, here called -qo2This unit is reduced with increasing age of the rat, and varies only slightly within an even age group of normal rats. in sublimate intoxicated rats, -qo2 has a close positive linear correlation to the specific gravity of the urine. in a series of rats given 4 mg sublimate per kg body weight, -qo2 was reduced to nearly one half of normal at the time of greatest polyuria. There was no morphological sign...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.