Abstract

Moringa oleifera, a fast-growing deciduous tree that is widely cultivated in tropical and subtropical regions of the world, is well known for its abundant uses. The tree is a source of food, shelter, and traditional medicine for many people, especially in developing countries. Many studies have been conducted to evaluate the various claims of traditional medicine practitioners that the moringa tree can improve health and treat various diseases. The tree has a high nutritional profile, especially the nutrient rich leaves. Some reports also support the use of parts of the tree to reduce blood sugar and cholesterol levels. These attractive properties have led researchers to look for other novel uses for the moringa tree, especially as a source of anticancer drugs. Researchers have tested extracts from various parts of the moringa tree both in vitro and in vivo on several types of cancers with varying success. This review explores the state of current research on the anticancer properties of M. oleifera.

Highlights

  • Moringa oleifera, better known as the drumstick tree or known as moringa, is native to the foothills of the Himalayan ranges in the Indian subcontinent [1]

  • The results showed that moringa leaf extracts had good anticancer activity in vitro against acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and HepG2 cells

  • Most of the research has focused on moringa leaf extracts, and the published results suggest that the extract is cytotoxic to a wide variety of different cancerous cells

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Summary

Introduction

Better known as the drumstick tree or known as moringa, is native to the foothills of the Himalayan ranges in the Indian subcontinent [1]. It is very hardy and adaptable to tropical and subtropical climates It can tolerate low water environments and requires minimal care to grow well, and it is common to see moringa trees planted as shade trees beside municipal roads in India and Southeast Asia. M. oleifera is a good candidate for agroforestry projects in tropical and subtropical climates due to its ease of cultivation and multiple uses [11] They can be used as a wind break and to prevent soil erosion. Blood test results and histopathological examination of liver sections showed that rats treated with moringa leaf extract recovered better from hepatic damage induced by antitubercular drugs than did untreated rats These findings support the use of moringa for some treatments used in traditional medicine. Scientific interest in the antitumor/anticancer activities of M. oleifera has been growing due to the increasing incidence of cancer, and this will be the main focus of our review

Natural Products as Anticancer Agents
Moringa Leaf Extract: A Potential Anticancer Agent
Experiments
Findings
Conclusion

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