Abstract

Medication-Related Osteonecrosis of the Jaw [MRONJ] is a rare but serious side effect caused by medications such as bisphosphonate and denosumab, which are used as antiresorptive medications in malignancies related to bone metastases and bone metabolism diseases. Since the major predisposing factor of this side effect may be tooth extraction, our aim in this review is to show that preventing the emergence of pathology in dental hard tissues and treating it when it occurs with a preventive and therapeutic strategy, providing adequate oral hygiene, and motivating the patient for its continuity could reduce the risk of the occurrence of MRONJ by reducing the need for oral surgery in terms of restorative dental treatment.

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