The Importance of Qualitative/Quantitative Analytical Tools in COVID-19 Vaccine Development

Abstract

The COVID-19 pandemic has resulted in significant morbidity and mortality worldwide, emphasizing the need for effective vaccines. The development of a COVID-19 vaccine requires extensive analysis to ensure its safety and efficacy. In this review, the importance of analytical tools in COVID-19 vaccine development was discussed. A comprehensive literature search using PubMed and Scopus was conducted. Analytical tools play a crucial role in COVID-19 vaccine development, from the initial stages of antigen characterization to vaccine formulation and efficacy testing. The tools used include immunoassay-based methods, separation-based methods, and microscopy. These tools facilitate the characterization of antigens, selection of adjuvants, optimization of formulation, and stability testing. Moreover, analytical tools enable the evaluation of vaccine safety and efficacy, which are necessary for regulatory approval. Therefore, the implementation of analytical tools in COVID-19 vaccine development is crucial in ensuring the timely and successful development of a vaccine to combat the pandemic.