Abstract
This retrospective study included 68 OSAS patients with coronary artery disease (CAD) who were followed up at Cardiology and Neurology Outpatient Clinic in our hospital between January 2019 and October 2020. Patients with previously diagnosed OSAS were separated into 2 groups as mild-moderate OSAS group (Group I) and severe OSAS group (Group II). In both groups, coronary angiography was examined using the SX score.
Highlights
Obstructive sleep apnea syndrome (OSAS) is a common disorder that manifests clinically as irregular snoring and sleep rhythm disorders
The results of the current study showed that severe OSAS patients are at higher risk of advanced cardiovascular disease with a higher SX score
There was no significant difference between the groups in respect of age, gender, smoking status, hyperlipidemia, BMI, hypertension and diabetes mellitus
Summary
Obstructive sleep apnea syndrome (OSAS) is a common disorder that manifests clinically as irregular snoring and sleep rhythm disorders. It is often accompanied by diseases such as hypertension, arrhythmia, chronic pulmonary hypertension, type 2 diabetes mellitus, stroke and coronary artery disease (CAD) [1,2,3]. In patients with OSAS, oxygen saturation in the blood decreases as a result of shortness of breath caused by recurrent upper respiratory tract constriction or obstruction during sleep. This causes a series of pathophysiological changes that result in inflammation, endothelial dysfunction, increased oxidative stress, and activation of the sympathetic system, and these may cause the onset of cardiovascular disease [9,10,11]. Even in some studies, the relationship between cardiovascular outcomes and OSAS remains unclear [12,13]
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