Abstract

The importance of leadless pacemaker positioning in relation to subcutaneous implantable cardioverter-defibrillator sensing in completely leadless cardiac resynchronization and defibrillation systems

Highlights

  • Leadless pacemakers and subcutaneous implantable cardioverter-defibrillators (S-ICDs) are attractive options to reduce the risks associated with transvenous systems, such as vascular access complications and recurrent lead infections, and their clinical use is increasing.[1,2] Leadless cardiac resynchronization therapy (CRT) can be delivered using the WiSE-CRT system (EBR Systems, Sunnyvale, CA), which improves symptoms and left ventricular (LV) remodeling in patients who are untreatable or nonresponders to conventional CRT.[3,4] This system uses ultrasound-based wireless communication between a submuscular transmitter and an endocardial electrode to deliver LV pacing, and requires an existing device capable of delivering continuous right ventricular (RV) pacing to achieve CRT

  • We report the case of a patient with a completely leadless CRT defibrillator system where implant of a new Micra leadless pacemaker resulted in an inappropriate shock from the subcutaneous implantable cardioverterdefibrillator (S-ICD)

  • Elliott et al Leadless Pacemaker Position and S-ICD Sensing in Leadless CRT-D Systems chronic kidney disease, persistent atrial fibrillation, and underlying complete heart block underwent implantation of a completely leadless primary prevention CRT defibrillator system after multiple previous device extractions for recurrent infections, as previously reported.[6]

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Summary

Introduction

Leadless pacemakers and subcutaneous implantable cardioverter-defibrillators (S-ICDs) are attractive options to reduce the risks associated with transvenous systems, such as vascular access complications and recurrent lead infections, and their clinical use is increasing.[1,2] Leadless cardiac resynchronization therapy (CRT) can be delivered using the WiSE-CRT system (EBR Systems, Sunnyvale, CA), which improves symptoms and left ventricular (LV) remodeling in patients who are untreatable or nonresponders to conventional CRT.[3,4] This system uses ultrasound-based wireless communication between a submuscular transmitter and an endocardial electrode to deliver LV pacing, and requires an existing device capable of delivering continuous right ventricular (RV) pacing to achieve CRT. A combination of the Micra leadless pacemaker (Medtronic, Fridely, MN) and the WISE-CRT system has demonstrated the feasibility to deliver leadless CRT5 and the addition of an S-ICD (Emblem S-ICD; Boston Scientific, Marlborough, MS) has demonstrated the ability to have a completely leadless CRT defibrillator system.[6] These devices are not designed to be used together, and co-implantation requires complex

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