Abstract

Applied In Vitro ToxicologyVol. 2, No. 1 Roundtable DiscussionThe Importance of In Vitro Liver Models: Experts Discuss Whole-Cell Systems, Transporter Function, and the Best Models for Future In Vitro TestingModerator: Kenneth R. Brouwer, Participants: Stephen S. Ferguson, Yurong Lai, Gang Luo, Amy L. Roe, Donna A. Volpe, and Kyunghee YangModerator: Kenneth R. BrouwerChief Scientific Officer, Qualyst Transporter Solutions Inc., Durham, North Carolina.Search for more papers by this author, Participants: Stephen S. FergusonChemist, Molecular Toxicology and Informatics Group, NIH/NIEHS, Durham, North Carolina.Search for more papers by this author, Yurong LaiSenior Principal Scientist, Pharmaceutical Candidate Optimization Department, Bristol-Myers Squibb, New York City, New York.Search for more papers by this author, Gang LuoLead Study Director, Covance Laboratories, Madison, Wisconsin.Search for more papers by this author, Amy L. RoeProduct Safety & Regulatory Affairs, The Procter & Gamble Company, Cincinnati, Ohio.Search for more papers by this author, Donna A. VolpeDivision of Applied Regulatory Science, Food & Drug Administration, Silver Spring, Maryland.*The findings, conclusions, and opinions expressed in this article have not been formally disseminated by the Food and Drug Administration and should not be construed to represent any agency determination or policy.Search for more papers by this author, and Kyunghee YangScientist, DILIsym Services Inc., Research Triangle Park, North Carolina.Search for more papers by this authorPublished Online:14 Mar 2016https://doi.org/10.1089/aivt.2016.29004.rtlAboutSectionsView articleView Full TextPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail View articleFiguresReferencesRelatedDetailsCited byCharacterisation of a functional rat hepatocyte spheroid modelToxicology in Vitro, Vol. 55The C-DILI™ Assay: An Integrated In Vitro Approach to Predict Cholestatic Hepatotoxicity24 April 2019Impact of cell types and culture methods on the functionality of in vitro liver systems – A review of cell systems for hepatotoxicity assessmentToxicology in Vitro, Vol. 48Translating New Science Into the Drug Review Process: The US FDA’s Division of Applied Regulatory Science30 December 2018 | Therapeutic Innovation & Regulatory Science, Vol. 52, No. 2 Volume 2Issue 1Mar 2016 InformationCopyright 2016, Mary Ann Liebert, Inc.To cite this article:Moderator:, Kenneth R. Brouwer, Participants:, Stephen S. Ferguson, Yurong Lai, Gang Luo, Amy L. Roe, Donna A. Volpe, and Kyunghee Yang.The Importance of In Vitro Liver Models: Experts Discuss Whole-Cell Systems, Transporter Function, and the Best Models for Future In Vitro Testing.Applied In Vitro Toxicology.Mar 2016.1-7.http://doi.org/10.1089/aivt.2016.29004.rtlPublished in Volume: 2 Issue 1: March 14, 2016PDF download

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