Abstract

The incidence and prevalence of Alzheimer's disease and related dementias continue to rise as life expectancy increases worldwide. If these diseases could be diagnosed accurately before symptom onset, strategies could be developed to protect brain neurodegeneration and enable endogenous and exogenous neuroplastic repair mechanisms to continue to maintain a sufficient level of cognitive function. However, a major hindrance to improving the diagnosis of Alzheimer's disease is that the aetiology remains unclear.

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