Abstract
Genome-wide sequencing (GWS) is the most sensitive test available for detecting pathogenic genetic variants. In line with guidelines in North America and Europe, best clinical practice requires GWS to be implemented as a holistic clinical service that includes both pre-test and post-test genetic counselling. Genome-wide sequencing (GWS) is the most sensitive test available for detecting pathogenic genetic variants but it generates complex results. It is important, therefore, that individuals undergoing GWS are offered both pre-test and post-test genetic counselling.
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