The Importance of Four-Finger Furrow in the Diagnosis of Pediatric Chromosomal Anomalies

Abstract

Since Langdon-Down in 1909 paid special attention to the special formation among the flexion furrows of the human hand, generally known as Affenfurche or Vierfingerfurche, in connection with the clinical picture of mongoloid idiocy, investigators have dealt with this subject again and again and from the most different points of view. Anthropologists were interested in the occurrence of this furrow form in humans and apes from a phylogenetic point of view.