Abstract

Alzheimer’s Disease (AD) and other dementias are prevalent neurodegenerative diseases characterized by decreased cognition, physical function, and quality of life. Currently, millions of people are living with AD and other dementias. With no cure, research has examined the use of non-pharmacological treatment options including exercise. Many high-quality studies demonstrate that physical activity slows the progression of AD’s many outcomes, and is beneficial to overall quality of life in those living with AD. However, creating exercise interventions at the community level that individuals will adhere to is often a challenge. The Alzheimer’s Society of Canada developed a unique program that combines physical activity with cognitive stimulation in a social atmosphere: The Minds in Motion® program. Minds in Motion® addresses many of the barriers often linked to poor physical activity participation in chronic diseases (such as inclusion of the care partner), to ensure the best program uptake. The Minds in Motion® program has anecdotally been successful in helping to increase physical function and social skills in those living with dementia. However, it is important to connect community-driven programs with the academic research community, to create an opportunity for high quality evaluation metrics that can be disseminated at multiple levels: to research audiences, clinical audiences, and to those in the community. With ongoing collaborations between research and community programs, there is a greater opportunity to understand the positive impact of a program, which ultimately increases the chance of funding for the program. In this editorial, we highlight that community-integrated research is an important priority for future collaborations.

Highlights

  • Alzheimer’s Disease (AD) and other dementias are prevalent neurodegenerative diseases characterized by decreased cognition, physical function, and quality of life

  • An interesting question emerges: does AD lead to poor physical function and/or poor physical activity participation? Or does reduced physical activity participation precede the diagnosis of AD? It is likely a combination of the two scenarios

  • The use of exercise as medicine has gained recent attention from researchers and clinicians [15,16] given the positive impact of exercise programs on various outcomes in chronic diseases such as cardiovascular diseases, cancer, obesity, depression, as well as in persons living with dementia [4,17,18,19,20]

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Summary

Introduction

Alzheimer’s Disease (AD) and other dementias are prevalent neurodegenerative diseases characterized by decreased cognition, physical function, and quality of life. Diagnosis of AD is associated with a subsequent decline in physical function [1,13], it may be a circular relationship whereby obesity, poor strength/gait are predictive of dementia onset, and that dementia (including AD) leads to further exacerbation of poor physical function, activity participation, and physical health.

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