Abstract
THE IMPORTANCE OF CLINICAL TARGET VOLUME FOR RADIATION THERAPY IN RECTAL CANCER (Abstract): Neoadjuvant chemoradiotherapy is the standard treatment in locally advanced rectal cancer and it was demonstrated that radiation therapy associated with total mesorectal excision reduces local recurrence rate. It is very important to precisely determine the area that is subjected to radiation, in order to avoid side effects. The clinical target volume (CTV) is dependent on tumor location, lymphatic drainage area and the degree of tumor invasion into nearby organs. The CTV determination must take into account the internal organ motion during the treatment. The radiotherapy simulating is possible due to specialized CT and/or MRI and planning software. Using this method, it is possible to modulate the intensity of radiation on tumor tissue, with minimal effects on normal tissues.
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