Abstract
Titanium alloys are known for their biological, mechanical and chemical properties, which have successfully expanded their use in the maxillofacial field. The internal fixation using titanium miniplates and screws offer a new perspective for the treatment of trauma and in orthognathic surgery and maxillofacial oncology. Although, titanium is highly recommended for its excellent biocompatibility, recent research has focused on identifying the potential local and general implications of the interactions between the human tissue and the metallic particles. This present review aims to outline the existing tissue changes, cellular alterations and future perspectives regarding the use of titanium-based alloys as osteosynthesis materials, taking into consideration the existing present debate whether the routinely removal of these materials should be an indication.
Highlights
Maxillofacial fractures represent a common pathology and a continuous challenge for clinicians.Among this particular pathology, the most frequent are the mandibular fractures that imply particular attention regarding the treatment by achieving a proper functionality and aesthetic outcome through the reconstruction of the local anatomy, occlusion and functional activity [1]
These results suggest an increased imbalance of the redox homeostasis and oxidative stress management associated to the patients with mandibular fractures that were treated with titanium alloys miniplates and screws
Our purpose was to identify the potential implications that titanium-based alloys used for maxillofacial osteosynthesis could have upon the local and general health
Summary
Maxillofacial fractures represent a common pathology and a continuous challenge for clinicians Among this particular pathology, the most frequent are the mandibular fractures that imply particular attention regarding the treatment by achieving a proper functionality and aesthetic outcome through the reconstruction of the local anatomy, occlusion and functional activity [1]. The most frequent are the mandibular fractures that imply particular attention regarding the treatment by achieving a proper functionality and aesthetic outcome through the reconstruction of the local anatomy, occlusion and functional activity [1] Injuries in this segment include hard and soft tissue alterations that could occur from the frontal area to the mandible [2]. The aetiology of these fractures includes a wide range of violence trauma, road traffic accidents, sport injuries, falls or work-related injuries [2,3]
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