Abstract
Corrigendum3 June 2014Open Access The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes Alessia Indrieri Alessia Indrieri Search for more papers by this author Ivan Conte Ivan Conte Search for more papers by this author Giancarlo Chesi Giancarlo Chesi Search for more papers by this author Alessia Romano Alessia Romano Search for more papers by this author Jade Quartararo Jade Quartararo Search for more papers by this author Rosarita Tatè Rosarita Tatè Search for more papers by this author Daniele Ghezzi Daniele Ghezzi Search for more papers by this author Massimo Zeviani Massimo Zeviani Search for more papers by this author Paola Goffrini Paola Goffrini Search for more papers by this author Ileana Ferrero Ileana Ferrero Search for more papers by this author Paola Bovolenta Paola Bovolenta Search for more papers by this author Brunella Franco Brunella Franco Search for more papers by this author Alessia Indrieri Alessia Indrieri Search for more papers by this author Ivan Conte Ivan Conte Search for more papers by this author Giancarlo Chesi Giancarlo Chesi Search for more papers by this author Alessia Romano Alessia Romano Search for more papers by this author Jade Quartararo Jade Quartararo Search for more papers by this author Rosarita Tatè Rosarita Tatè Search for more papers by this author Daniele Ghezzi Daniele Ghezzi Search for more papers by this author Massimo Zeviani Massimo Zeviani Search for more papers by this author Paola Goffrini Paola Goffrini Search for more papers by this author Ileana Ferrero Ileana Ferrero Search for more papers by this author Paola Bovolenta Paola Bovolenta Search for more papers by this author Brunella Franco Brunella Franco Search for more papers by this author Author Information Alessia Indrieri, Ivan Conte, Giancarlo Chesi, Alessia Romano, Jade Quartararo, Rosarita Tatè, Daniele Ghezzi, Massimo Zeviani, Paola Goffrini, Ileana Ferrero, Paola Bovolenta and Brunella Franco EMBO Mol Med (2014)6:849-849https://doi.org/10.15252/emmm.201470060 This article corrects the following: The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes13 December 2012 ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info In the above article, holo-cytochrome c-type synthase was used instead of holocytochrome c-type synthase, the official gene name. This error occurs in three places in the text and the correct sentences should read: In the abstract: Now we provide the evidence that non-canonical mitochondrial-dependent apoptosis explains the phenotype of microphthalmia with linear skin lesions (MLS), an X-linked developmental disorder caused by mutations in the holocytochrome c-type synthase (HCCS) gene. In the introduction: HCCS is a highly conserved gene from fungi to metazoans and encodes a mitochondrial holocytochrome c (Cytc)-type synthase, also known as ‘heme lyase’, located on the outer surface of the inner mitochondrial membrane (Schaefer et al, 1996; Schwarz & Cox, 2002). In ‘The paper explained’ section: We demonstrate that inactivation of holocytochrome c-type synthase (HCCS), a transcript important for the mitochondrial respiratory chain (MRC), is associated with unconventional activation of caspase-9 in the mitochondria triggered by MRC impairment and overproduction of reactive oxygen species. Next ArticlePrevious Article Volume 6Issue 61 June 2014In this issue RelatedDetailsLoading ...
Highlights
In the above article, holo-cytochrome c-type synthase was used instead of holocytochrome c-type synthase, the official gene name
The impairment of holocytochrome c-type synthase (HCCS) leads to microphthalmia with linear skin lesions (MLS) syndrome by activating a non-canonical cell death pathway in the brain and eyes
Holo-cytochrome c-type synthase was used instead of holocytochrome c-type synthase, the official gene name. This error occurs in three places in the text and the correct sentences should read: In the abstract: we provide the evidence that non-canonical mitochondrialdependent apoptosis explains the phenotype of microphthalmia with linear skin lesions (MLS), an X-linked developmental disorder caused by mutations in the holocytochrome c-type synthase (HCCS) gene
Summary
Holo-cytochrome c-type synthase was used instead of holocytochrome c-type synthase, the official gene name.
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