Abstract
Introduction: Cancer diagnosis can have a profound negative impact on the health-related quality of life (HRQoL) of cancer patients. Cancer patients also suffer from psychological pressures including sadness, depression, hopelessness, anxiety and worry. The literature review was employed to determine the effects of depression on health-related quality of life (HRQoL) in cancer patients.Methods: A systematic review was conducted by searching the Science Direct, Scopus and Google Scholar databases. The integrative review of the 10 articles was focused on the 10 years period from 2008 to 2018. The language used was English and the search was conducted using predefined keywords.Results: All of the journals discussed the impact of depression treatment on health-related quality of life in cancer patients. Based on all of the journals, depression can be reduced by health education, physical activity and medicine therapyConclusion: Despite the treatment for depression, the patient’s HRQoL did not improve during the measurement timeframe. Quality of life is a priority health outcome in cancer treatment but the clinical approaches to ameliorate depression in cancer patients appear to be suboptimal.
Highlights
Cancer diagnosis can have a profound negative impact on the health-related quality of life (HRQoL) of cancer patients
All of the journals discussed the impact of depression treatment on health-related quality of life in cancer patients
This study aims to determine the effects of pharmacological and non-pharmacological therapies on reducing the depression in cancer patients so as to increase HRQoL
Summary
Cancer diagnosis can have a profound negative impact on the health-related quality of life (HRQoL) of cancer patients. The literature review was employed to determine the effects of depression on health-related quality of life (HRQoL) in cancer patients. Comorbid depression in adults with cancer is negatively associated with health-related quality of life (HRQoL), which, in turn, may decrease survival. To improve HRQoL and survival in this vulnerable group, adults with cancer and comorbid depression should be offered pharmacological or psychological treatment for depression. The importance of detecting and treating depressive illness in cancer patients lies in the relief of the psychological distress and its impact on quality of life and on the consequent health service and societal costs. Depression has been associated with the increased impairment of the human immune response and poorer survival
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