The Impact of the Protocol of Central Line Bundle Care on Catheter Related Blood Stream Infection

Abstract

Hospital acquired infection is a serious problem in the intensive care unit, and a major cause of morbidity and mortality of Intensive Care Unit patients. Application of the central line bundle has demonstrated striking reduction in the rate of catheter infections in hospitals. This study aimed to determine the impact of central line bundle care on catheter associated blood stream infection. Prospective randomized blinded clinical trial was performed. Sixty patients were randomly allocated into two groups. Group I: (n=30) patients who underwent catheter insertion using hospital procedure for central line and antibiotic coated catheter, Group II: (n=30) patients who underwent catheter insertion using bundle care protocol and silver coated catheter. Mean duration of catheters in bundle cared group were 11.07 ± 4.9 days while 11.4 ± 4.3 days in hospital technique group. Colonization was detected in 78.6% of antibiotic coated catheter (Group I) and 21.4% of silver coated catheter (Group II). Common microorganisms were 25.20% Acinetobacter, 24.39% Klebsiella, and 12.20% Staphylococcus epidermidis. Applications of bundle care protocol for Central Venous Catheter reduce the incidence rate of catheter-related infection. Furthermore, the use of silvercoated Central Venous Catheter is superior to antimicrobial-coated catheter in the prevention of catheter related infection.